Appears I misled us. The IronPython.Modules assembly was not getting copied to bin but not the directly the app was actually running from.
at the top of the class and the assembly is loaded the and errno error is gone.
I'm able to execute scripts now pretty easily, and am hitting a Syntax Error when importing jinja2 like you mentioned:
Tried a number of searches and tweaks. Do you have more specific knowledge on what needs to be patched to enable jinja2? Does it require a specific verson? We're currently targeting 2.10
Thanks for your help!